Prior to the first intravenous Infed therapeutic dose, administer an intravenous test dose of 0.5 mL [see BOXED WARNING and Warnings and Precautions (5.1)]. Infed (Iron Dextran): Uses, Dosage, Side Effects, Interactions - RxList Administer a test dose of Infed prior to the first therapeutic dose [see Dosage and Administration (2.4)]. I1US99`^cc-G:>xzV5.tD8,D\>z;qxQ)bHV\c`BWNG ni*#gU4yv{J)!VMs12EJR4>43giIU?H(MlJW52 &&RBd2i%d)jUWfk$oQs=@a+~cl 0000030666 00000 n The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). This reference contains standard dilutions including IV admixture drug concentration, infusion volumes, and infusion rates. Medical Communications Stability of solutions of antineoplastic agents during preparation and storage for in vitro assays. Specific Populations %PDF-1.4 % 0000006695 00000 n BILy@yK5] I(Y+ u YV ;bPqZ9~3oG RqK|"@k!/<9 .*JIr|R$ck4w8Szd*-qK"#AgFIyVsT`PtP_-tO=jq"~.^^2={nZU$ , Bethesda, MD 20894, Web Policies Take precautions to be prepared to treat potential allergic reactions. Discontinue administration of any iron-containing products prior to administration of Infed. Initial U.S. Approval: 1974 INFeD may be used alone or with other medications. Following intramuscular administration, Infed is absorbed from the injection site into the capillaries and the lymphatic system. Your comment will be reviewed and published at the journal's discretion. INDICATIONS AND USAGE: Injectafer is indicated for the treatment of iron deficiency anemia in adult patients: >who have intolerance to oral iron or have had unsatisfactory response to oral iron; . There are no data on the effects of iron dextran in breastfed infants or effects on milk production. 1995; 26(2):327-330. Clipboard, Search History, and several other advanced features are temporarily unavailable. Such iron overload is particularly apt to occur in patients with hemoglobinopathies and other refractory anemias that might be erroneously diagnosed as iron deficiency anemias. . Large intravenous doses, such as used with total dose infusions (TDI), have been associated with an increased incidence of adverse reactions. ], Observed Hb = the patients current hemoglobin in g/dL. Would you like email updates of new search results? Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever the solution and container permit. A patients lean body weight (or actual body weight if less than lean body weight) should be utilized when determining dosage. After reconstitution with 19 ml water for injections, the product contains 10 mg/ml voriconazole and 160 mg/ml SBECD. 8.4 Pediatric Use Anaphylaxis and other hypersensitivity reactions have been reported after uneventful test doses as well as therapeutic doses of iron dextran injection. . 0000006673 00000 n (See Boxed Warning.) After slow IV injection (given over 30 seconds for INFeD or 5 minutes for Dexferrum) or IM injection (INFeD) of 25 mg of iron (0.5 mL), observe for 1 hour for sensitivity reactions (see Anaphylaxis under Cautions) before administering the remaining portion of the initial dose. All Rights Reserved. Store at 20C to 25C (68F to 77F); excursions permitted to 15C to 30C (59F to 86F). PDF HIGHLIGHTS OF PRESCRIBING INFORMATION ZEPZELCA, periodically during
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