Strain name in black/red indicates Aspergillus fumigatus resistant/susceptible. Ragout identifies large conserved regions between genomes (hierarchical synteny blocks) by combining the whole genome alignment with a de Bruijn graph simplification algorithm66. The care and use of mice in the study was carried out in accordance with UK Home Office regulations, UK Animals (Scientific Procedures) Act of 1986 under a UK Home Office license that approved this work, which was reviewed regularly by the WTSI Animal Welfare and Ethical Review Body. Sequential anaerobic-aerobic degradation of munitions waste. What Strain is Headspace? Effects & Flavors | The Weed Street Park, N. et al. The research leading to these results has received funding from the European Unions Seventh Framework Programme (FP7/20072013) under grant agreement HEALTH-F4-2010-241504 (EURATRANS). Neuroanatomical studies were performed blind with experimenters not knowing the genotype of the mouse, on three 16-week-old matched control male mice in C57BL/6N background and three 16-week-old homozygous knockout of Efcab3. One precise sagittal section was stereostatically defined as the plane Lateral +0.72 mm of the Mouse Brain Atlas. Bruce Banner specifically, its #3 phenotype offers incredible levels of THC and packs a punch that could humble even the most seasoned veteran. d, A regional dot plot of the Nlrp1 locus in PWK/PhJ compared to the C57BL/6J GRCm38 reference (color-coded same as panel c). For the first time, it shows the order, orientation, and structure of three highly divergent haplotypes present in WSB/EiJ, PWK/PhJ, and SPRET/EiJ, including novel annotation of rearranged promoters, inserted processed pseudogenes, and a high frequency of LINE repeats (Supplementary Data 6). Genetic and haplotype diversity among wild-derived mouse inbred strains. Nature 537, 508514 (2016). Learn about safe consumption, the impact of legalization, and how you can join the festivities! 1d, right). Bookshelf We have completed the first draft de novo assemblies and strain-specific gene annotation for 12 classical inbred laboratory mouse strains (129S1/SvImJ, A/J, AKR/J, BALB/cJ, C3H/HeJ, C57BL/6NJ, CBA/J, DBA/2J, FVB/NJ, LP/J, NZO/HlLtJ, and NOD/ShiLtJ) and 4 wild-derived strains representing the backgrounds Mus musculus castaneus (CAST/EiJ), M. m. musculus (PWK/PhJ), M. m. domesticus (WSB/EiJ), and M. spretus (SPRET/EiJ). is supported by R01 DK074656. Initial sequencing and comparative analysis of the mouse genome. Collaborative Cross mice and their power to map host susceptibility to Aspergillus fumigatus infection. Thanks a lot for sharing your opinion! We examined the strain-specific RNA-Seq (Comparative Augustus) gene predictions containing 75% novel introns compared to the existing reference annotation (Table 1) (GENCODE M8, chromosomes 112). hybrid. 2017 Apr;6(2):e00423. This strain has become popular for its libido-boosting effects that will put you in the mood for romance. Hpcal1 belongs to the neuronal calcium sensors expressed primarily in retinal photoreceptors, neurons, and neuroendocrine cells34. Combinatorial effects of odorants on mouse behavior. Indica strains are known for their relaxing and calming effects, often used for stress relief and relaxation. Provided by the Springer Nature SharedIt content-sharing initiative, Nature Genetics (Nat Genet)
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