Pre-filled flush syringe can be used in place of traditional sealing fluids such as normal saline. The novel tube sealing solution has a wide range of applications, is simple to operate, has small limitations, and has little impact on the patient’s condition and physiological indicators. The pre-filled flush syringe can complete the preparation of some drugs before infusion, reduce the consumption of heavy materials and facilitate storage. Pre-filled flush syringe can reduce the chance of contamination, reduce the risk of infection, high safety, avoid needle stick injuries of medical staff, and reduce operation time. Pre-filled flush syringe is the first choice for clinical flushing and sealing.